hCAI/II-IN-9

hCAI/II-IN-9

• CAS Number: 175014-68-3
• UNSPSC Description: hCAI/II-IN-9 is a carbonic anhydrase inhibitor with inhibitory activity against human carbonic anhydrase isoforms I, II, IX, and XII. The inhibition constants (Ki) of hCAI/II-IN-9 for hCA I are in the range of 7.9-894 nM, for hCA II are in the range of 7.5-1645 nM, for hCA IX are in the range of 5.0-240 nM, and for hCA XII are in the range of 0.47-2.83 nM. hCAI/II-IN-9 may have potential applications in inhibiting a variety of pathologies involving these carbonic anhydrase isoforms[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/hcai-ii-in-9.html
• Smiles: O=S(C1=CC=C(NC(NC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)(N)=O
• Molecular Weight: 336.32
• References & Citations: [1]Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported