FAAH-IN-5

• Description :

  FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability[1].

• CAS Number :

  [1338575-38-4]

• UNSPSC :

  12352005

• Target :

  FAAH; MAGL

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/faah-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCN(CC1)S(=O)(C2=CC=C3C=CC=CC3=C2)=O)OC4=CC=C(C=C4)[N+]([O-])=O

• Molecular Formula :

  C21H19N3O6S

• Molecular Weight :

  441.46

• References & Citations :

  [1]Alan Fulp, et al. Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. Bioorg Med Chem Lett. 2022 Jul 15;68:128763.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported