MIF-IN-5

• UNSPSC Description:

  MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].

• Target Antigen:

  Macrophage migration inhibitory factor (MIF)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mif-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCC1=CN(N=N1)C2=CC(F)=C(C=C2)O)C3=CC4=CC=CC=C4N3

• Molecular Weight:

  351.33

• References & Citations:

  [1]Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2582755-31-3