MIF-IN-5

MIF-IN-5

• CAS Number: 2582755-31-3
• UNSPSC Description: MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].
• Target Antigen: Macrophage migration inhibitory factor (MIF)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/mif-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCC1=CN(N=N1)C2=CC(F)=C(C=C2)O)C3=CC4=CC=CC=C4N3
• Molecular Weight: 351.33
• References & Citations: [1]Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported