CD22 ligand-1

• Description :

  CD22 ligand-1 (compound 12) is a potent and selective CD22 ligand with KD of 0.335, 30.7 µM for hCD22 and MAG, respectively. CD22 ligand-1 has the potential for the research of B-cell related disease[1].

• CAS Number :

  [2493080-27-4]

• UNSPSC :

  12352005

• Target :

  CD22

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cd22-ligand-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@]1(N2C=C(C3=CC=CC=C3)N=N2)O[C@@]([C@@H]([C@H](C1)O)NC(CO)=O)([H])[C@H](O)[C@H](O)CNC(CC4=CC=C(C5=CC=C(C=C5)O)C=C4)=O)O[Na]

• Molecular Formula :

  C33H34N5NaO10

• Molecular Weight :

  683.64

• References & Citations :

  [1]Abdu-Allah HHM, et al. Design, synthesis and molecular docking study of α-triazolylsialosides as non-hydrolyzable and potent CD22 ligands. Eur J Med Chem. 2020 Dec 15;208:112707.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported