Elastase-IN-1

• UNSPSC Description:

  Elastase-IN-1 (Compound Q11) is an elastase inhibitor with an IC50 of 0.897 µM. Elastase-IN-1 is non-toxic[1].

• Target Antigen:

  Elastase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/elastase-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C/C1=NC2=CC=CC=C2C=C1)C3=CC=C([N+]([O-])=O)C=C3

• Molecular Weight:

  320.30

• References & Citations:

  [1]Vanjare BD, et al. Elastase inhibitory activity of quinoline Analogues: Synthesis, kinetic mechanism, cytotoxicity, chemoinformatics and molecular docking studies. Bioorg Med Chem. 2022 Jun 1;63:116745.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  678152-73-3