Elastase-IN-3

• Description :

  Elastase-IN-3 (Compound 2i) is an Elastase inhibitor of Pseudomonas aeruginosa. Elastase-IN-3 inhibits the quorum sensing system of Pseudomonas aeruginosa by targeting the LasR protein (KD value of 7.04 M), thereby preventing food spoilage caused by Pseudomonas aeruginosa[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Antibiotic; Bacterial; Elastase

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/elastase-in-3.html

• Purity :

  99.71

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  OC(C=C1)=CC=C1SSC2=CC=C(O)C=C2

• Molecular Formula :

  C12H10O2S2

• Molecular Weight :

  250.34

• Precautions :

  H315, H319

• References & Citations :

  [1]Zhang ZS, et al. Structure-Based Discovery of Symmetric Disulfides from Garlic Extract as Pseudomonas aeruginosa Quorum Sensing Inhibitors. J Agric Food Chem. 2024 Sep 4.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [15015-57-3]