Elastase, Human leukocytes

• UNSPSC Description:

  Elastase, Human leukocytes is a serine protease present in the nitrogen-loving granules of neutrophils. Elastase, Human leukocytes potential substrates include almost all components of the extracellular matrix, as well as a variety of proteins such as coagulation factors, complement, immunoglobulins and cytokines. It has a strong proteolytic function and participates in the pathogenesis of inflammatory tissue damage[1][2].

• Target Antigen:

  Others

• Type:

  Enzyme

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/elastase-human-leukocytes.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Elastase, Human leukocytes]

• References & Citations:

  [1]W L Lee, et al. Leukocyte elastase: physiological functions and role in acute lung injury. Am J Respir Crit Care Med. 2001 Sep 1;164(5):896-904.|[2]Tom Macleod, et al. Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist. Sci Rep. 2016 Apr 22:6:24880.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20°C for 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  9004-06-2