β-Nor-lapachone

• Description :

  β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].

• UNSPSC :

  12352005

• Target :

  Fungal; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/β-nor-lapachone.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2OC(C)(C)C1)C(C3=C2C=CC=C3)=O

• Molecular Formula :

  C14H12O3

• Molecular Weight :

  228.24

• References & Citations :

  [1]Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [52436-88-1]