β-Nor-lapachone

• Description:

  β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/β-nor-lapachone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (C1=C2OC (C) (C) C1) C (C3=C2C=CC=C3) =O

• Molecular Formula:

  C14H12O3

• Molecular Weight:

  228.24

• References & Citations:

  [1]Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  52436-88-1