9-Hydroxy-α-lapachone

• UNSPSC Description:

  9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells[1].

• Target Antigen:

  NO Synthase

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/9-hydroxy-α-lapachone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3

• Molecular Weight:

  258.27

• References & Citations:

  [1]Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  22333-58-0