9-Hydroxy-α-lapachone

• Description :

  9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells[1].

• Product Name Alternative :

  α-Dihydrocaryopterone

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  NO Synthase

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/9-hydroxy-α-lapachone.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3

• Molecular Formula :

  C15H14O4

• Molecular Weight :

  258.27

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33 (3) :381-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [22333-58-0]