9-Hydroxy-α-lapachone

CAT: 0804-HY-N2794Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N2794Size:1 Each
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Description
9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells[1].
CAS Number
[22333-58-0]
Product Name Alternative
α-Dihydrocaryopterone
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/9-hydroxy-α-lapachone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3
Molecular Formula
C15H14O4
Molecular Weight
258.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33 (3) :381-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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