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EV-A71-IN-1

CAT: 0804-HY-145850Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145850Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM) [1].
CAS Number
2413648-96-9
UNSPSC
12352005
Target
Enterovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ev-a71-in-1.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC=C(C=C2)NC3=NC(C4=CN=C5N=CC=CN45)=CS3)=CC=CC=C1
Molecular Formula
C21H15N5S
Molecular Weight
369.44
References & Citations
[1]Xu Z, et al. Discovery of aminothiazole derivatives as novel human enterovirus A71 capsid protein inhibitors. Bioorg Chem. 2022;122:105683.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

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T61462-01EV-A71-IN-1
GTR19238069-01EV-A71-IN-2
T205180-01EV-A71-IN-3
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