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DX2-201

CAT: 0804-HY-145303Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145303Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DX2-201 is a potent and selective oxidative phosphorylation (OXPHOS) complex I inhibitor with an IC50 of 312 nM. DX2-201 has anticancer effects[1].
CAS Number
2749554-00-3
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dx2-201.html
Solubility
10 mM in DMSO
Smiles
O=S(N1C[C@@H](CCC1)C(OCC)=O)(C2=CC=C(C=C2)S(N(CC)CC)(=O)=O)=O
Molecular Formula
C18H28N2O6S2
Molecular Weight
432.55
References & Citations
[1]Ding Xue, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors.J Med Chem. 2022 Jan 13;65 (1) :343-368. https://pubmed.ncbi.nlm.nih.gov/34982568/
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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