DX2-201

• Description :

  DX2-201 is a potent and selective oxidative phosphorylation (OXPHOS) complex I inhibitor with an IC50 of 312 nM. DX2-201 has anticancer effects[1].

• UNSPSC :

  12352005

• Target :

  Mitochondrial Metabolism; Oxidative Phosphorylation

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dx2-201.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(N1C[C@@H](CCC1)C(OCC)=O)(C2=CC=C(C=C2)S(N(CC)CC)(=O)=O)=O

• Molecular Formula :

  C18H28N2O6S2

• Molecular Weight :

  432.55

• References & Citations :

  [1]Ding Xue, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors.J Med Chem. 2022 Jan 13;65 (1) :343-368. https://pubmed.ncbi.nlm.nih.gov/34982568/

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2749554-00-3]