PROTAC ERα Y537S degrader-1

PROTAC ERα Y537S degrader-1

• CAS Number: 2667598-05-0
• UNSPSC Description: PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Y537S degrader-1 extracts from patent WO2021143822, example 12. PROTAC ERα Y537S degrader-1 is an estrogen receptor-alpha (ERα) Y537S degrader[1].
• Target Antigen: Estrogen Receptor/ERR; PROTACs
• Type: Reference compound
• Related Pathways: PROTAC;Vitamin D Related/Nuclear Receptor
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-erα-y537s-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(CN1C3C(NC(CC3)=O)=O)C=C(N4CCN(CC4)CC5CCN(C6=CC=C([C@]7([H])C8=CC=C(O)C=C8CC[C@]7([H])C9=CC=CC=C9)C=C6)CC5)C%10=C2OCO%10
• Molecular Weight: 767.91
• References & Citations: [1]Yang FL, et, al. Bicyclic imide derivative, preparation method thereof, and application thereof in medicine. WO2021143822A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported