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IDO1-IN-16

CAT: 0804-HY-144466Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144466Size:1 Each
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Description
IDO1-IN-16 (I-1) is an IDO1 inhibitor targeting holo-IDO1, with an IC50 of 127 nM[1].
CAS Number
2677054-63-4
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCC)NC1=CC(/C(NO)=N\C2=CC=C(C(Br)=C2)F)=CC=C1N(CC(C)C)CC(C)C
Molecular Formula
C25H35BrFN5O2
Molecular Weight
536.48
References & Citations
[1]Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1

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