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IDO1-IN-15

CAT: 0804-HY-144465Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144465Size:1 Each
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Description
IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM) . IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat[1].
CAS Number
2126853-17-4
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-15.html
Solubility
10 mM in DMSO
Smiles
CCCNC(NC1=NON=C1/C(NC2=CC=C(C(Br)=C2)F)=N/O)=O
Molecular Formula
C13H14BrFN6O3
Molecular Weight
401.19
References & Citations
[1]Wu Y, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021;52:128373.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1

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