Bcl-2/Mcl-1-IN-3
CAT:
804-HY-144431
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Bcl-2/Mcl-1-IN-3
- CAS Number: 2088981-53-5
- UNSPSC Description: Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer[1].
- Target Antigen: Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bcl-2-mcl-1-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(O)C1=CC=CC=C1COC2=CC=CC3=C2C=CN3CCCOC4=CC(C)=C(Cl)C(C)=C4
- Molecular Weight: 463.95
- References & Citations: [1]Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported