Bcl-2/Mcl-1-IN-3

• UNSPSC Description:

  Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with Kis of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer[1].

• Target Antigen:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcl-2-mcl-1-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C1=CC=CC=C1COC2=CC=CC3=C2C=CN3CCCOC4=CC(C)=C(Cl)C(C)=C4

• Molecular Weight:

  463.95

• References & Citations:

  [1]Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2088981-53-5