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OXPHOS-IN-1

CAT: 0804-HY-144311Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144311Size:1 Each
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Description
OXPHOS-IN-1 (compound 2) is a oxidative phosphorylation (OXPHOS) inhibitor. OXPHOS-IN-1 inhibits the cells growth of MIA PaCa-2 and BxPC-3 cells with IC50s of 2.34 μM and 13.82 μM, respectively[1].
CAS Number
2749554-48-9
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxphos-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1CN(S(=O)(C2=CC=C(S(=O)(N(CC)CC)=O)C=C2)=O)CCC1)NC3COC3
Molecular Formula
C19H29N3O6S2
Molecular Weight
459.58
References & Citations
[1]Ding Xue, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022 Feb 24;65 (4) :3404-3419.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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