Pan-Trk-IN-2

Pan-Trk-IN-2

• CAS Number: 2583778-77-0
• UNSPSC Description: Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].
• Target Antigen: Trk Receptor
• Type: Reference compound
• Related Pathways: Neuronal Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pan-trk-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(NC(N=CN=C3N4)=C3OC(C)(C)C4=O)C=C2
• Molecular Weight: 506.86
• References & Citations: [1]Pan S,et al. Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants. J Med Chem. 2022 Feb 10;65(3):2035-2058.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported