Products for Research Use Only
RegisterLogin

NN-390

CAT: 0804-HY-143877-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-143877-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NN-390 is a potent and selective HDAC6 inhibitor, with an IC50 of 9.8 nM. NN-390 penetrates the blood-brain barrier (BBB) . NN-390 shows study potential in metastatic Group 3 MB (medulloblastoma) [1].
CAS Number
2490284-25-6
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nn-390.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)C1=CC=C(CN(C(C)C)S(=O)(C2=CC(F)=C(F)C(F)=C2F)=O)C=C1
Molecular Formula
C17H16F4N2O4S
Molecular Weight
420.38
References & Citations
[1]Nawar N, Bukhari S, Adile AA, et al. Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma. J Med Chem. 2022;65 (4) :3193-3217.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC11; HDAC2; HDAC3; HDAC6; HDAC8

Related Products

CatalogName
HY-P991293NN-2101
HY-169225-01PDIC-NN
HY-P991271-01NN-8828
HY-W040276Diafen NN
HY-169225APDIC-NN (dimethanesulfonate)
HY-W040276RDiafen NN (Standard)
HY-D1915-01ATTO 390
HY-148236-01BAY-390
HY-111793-01NUCC-390
HY-107761JMV 390-1

Alternative Products

CatalogName
GTR19186393-01NN-390
S-1529NN-Diethylethanolamine
S-1597NN-Dimethylacetamide
OR1043909-01NN-Diacetylmethylamine
OR1043753NN'-Diethyloxamide
OR1043685-01NN-Dibutylacrylamide
P29521PLR-NN
GTR19199304-01Diafen NN
T9901A-1718-01NN-8828
OR1043917-01NN-Dimethyldodecanamide

Popular Products