Products for Research Use Only

POP-3MB

CAT: 0013-GTR19234744-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234744-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
POP-3MB (compound 1b) is a potent ICMT inhibitor with an IC50 of 2.5 μM. It disrupts K-Ras membrane localization, suppresses Ras activation, and blocks downstream Erk phosphorylation. This tool compound is valuable for studying Ras-driven oncogenesis in both cellular and animal models of cancer.
CAS Number
1144114-27-1
Field of Research
Metabolism Research, Signal Transduction
Smiles
O (C1=C (C (N[C@@H] (CSCC=C (CCC2=CC=C (C=C2) C3=CC=CC=C3) CC=C (C) C) C (O) =O) =O) C=CC=C1) C4=CC=CC=C4
Molecular Formula
C38H39NO4S
Molecular Weight
605.79
Storage Conditions
-20°C
Notes
For research use only.

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