Germination-IN-2

• Description :

  Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/germination-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NC3=CC=CC=C3)=O)([H])[C@@]4([H])[C@@](C[C@@H]1O)([H])[C@@]5([C@](C[C@@H](CC5)O)([H])CC4)C

• Molecular Formula :

  C30H45NO3

• Molecular Weight :

  467.68

• References & Citations :

  [1]Sharma SK, et al. Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Bioorg Med Chem. 2021 Dec 15;52:116503.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [89846-43-5]