Germination-IN-1

Germination-IN-1

• CAS Number: 65384-76-1
• UNSPSC Description: Germination-IN-1 (compound 11) is a potent germination inhibitor with an IC50 of 4 µM. Germination-IN-2 shows anti-germination activity with 14% germination rate[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/germination-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NC3=CC=CC=C3)=O)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5([C@](C[C@@H](CC5)O)([H])C[C@H]4O)C
• Molecular Weight: 467.68
• References & Citations: [1]Sharma SK, et al. Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Bioorg Med Chem. 2021 Dec 15;52:116503.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported