NTPDase-IN-3

NTPDase-IN-3

• CAS Number: 2883147-45-1
• UNSPSC Description: NTPDase-IN-3 (Compound 5e) is a NTPDase inhibitor, with IC50 values of: 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). NTPDase-IN-3 can be used in the research of cancers and thrombosis[1].
• Target Antigen: NTPDase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/ntpdase-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: CC(CC1=CC=C(C=C1)C(C(NC2=NN=C(S2)SCC3=CC=C(C=C3)Cl)=O)C)C
• Molecular Weight: 446.03
• References & Citations: [1]Sadia Abbas, et al. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. Bioorg Chem. 2022 Jan;118:105456.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported