h-NTPDase8-IN-1

h-NTPDase8-IN-1

• CAS Number: 716358-51-9
• UNSPSC Description: h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1].
• Target Antigen: NTPDase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/h-ntpdase8-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)C1=CC(S(=O)(NC2CC2)=O)=CC=C1Cl
• Molecular Weight: 275.71
• References & Citations: [1]Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported