Products for Research Use Only

LMP7-IN-1

CAT: 0804-HY-142920Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-142920Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LMP7-IN-1, a Boronic acid derivative, is a potent and selective immunoproteasome subunit LMP7 (β5i) inhibitor with an IC50 of 1.83 nM (WO2021143923A1; compound 20) [1].
CAS Number
2671040-07-4
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lmp7-in-1.html
Solubility
10 mM in DMSO
Smiles
CN=S(C(C=CC=C1)=C1COC(N[C@H](B(O)O)CC2=COC3=CC=CC=C23)=O)(C)=O
Molecular Formula
C20H23BN2O6S
Molecular Weight
430.28
References & Citations
[1]Xianxing Shang, et al. Boronic acid derivatives. WO2021143923A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported