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PDE2A-IN-1

CAT: 0804-HY-142660Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142660Size:1 Each
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Description
PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC50 value of 1.3 nM.
CAS Number
2648290-28-0
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pde2a-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1[C@](CN(C2=CC(C3=CC=CC=C3)=CC=N2)CC1)([H])C4=CC(C(F)F)=NC5=NC=NN45
Molecular Formula
C23H22F2N6
Molecular Weight
420.46
References & Citations
[1]Tresadern G, et al. [1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration. J Med Chem. 2020 Nov 12;63 (21) :12887-12910.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE2

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