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(R) -GNE-274

CAT: 0804-HY-141551BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-141551BSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader) [1].
UNSPSC
12352005
Target
Drug Isomer
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-gne-274.html
Solubility
10 mM in DMSO
Smiles
CCCN1CC(C1)COC2=CC=C([C@H]3OC4=CC=C(C=C4C(C)=C3C5=CC(O)=CC=C5)O)C=C2
Molecular Formula
C29H31NO4
Molecular Weight
457.56
References & Citations
[1]Guan J, et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility. Cell. 2019 Aug 8;178 (4) :949-963.e18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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