Products for Research Use Only
RegisterLogin

N-Methyl-N'- (hydroxy-PEG2) -Cy5

CAT: 0804-HY-141072Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-141072Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
N-Methyl-N'- (hydroxy-PEG2) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
CAS Number
2107273-22-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-methyl-n-hydroxy-peg2-cy5.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C2=C(C=CC=C2)[N+](CCOCCOCCO)=C1/C=C/C=C/C=C3C(C)(C)C(C=CC=C4)=C4N\3C.[Cl-]
Molecular Formula
C32H41ClN2O3
Molecular Weight
537.13
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

Chemical Information

2-[2-[2-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]ethoxy]ethoxy]ethanol chloride
CAS Number2107273-22-1
PubChem CID166641745
IUPAC Name2-[2-[2-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]ethoxy]ethoxy]ethanol chloride
Molecular FormulaC32H41ClN2O3
Molecular Weight537.1
Topological Polar Surface Area44.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count11
Heavy Atom Count38
Formal Charge0
Complexity884
SMILES
CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C\3/C(C4=CC=CC=C4N3CCOCCOCCO)(C)C)C)C.[Cl-]
InChI
InChI=1S/C32H41N2O3.ClH/c1-31(2)25-13-9-11-15-27(25)33(5)29(31)17-7-6-8-18-30-32(3,4)26-14-10-12-16-28(26)34(30)19-21-36-23-24-37-22-20-35;/h6-18,35H,19-24H2,1-5H3;1H/q+1;/p-1
InChIKey
NEMABWCDKYHROP-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of 2-[2-[2-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]ethoxy]ethoxy]ethanol chloride
CAS: 2107273-22-1
CID: 166641745
Formula: C32H41ClN2O3
MW: 537.1
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight537.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count11
Exact Mass536.2805709
Monoisotopic Mass536.2805709
Topological Polar Surface Area44.9 Ų
Heavy Atom Count38
Formal Charge0
Complexity884
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-141073N- (m-PEG4) -N'- (hydroxy-PEG2) -Cy5
HY-141062N-Methyl-N'- (azido-PEG2-C5) -Cy5
HY-141035N- (m-PEG4) -N'- (PEG2-acid) -Cy5
HY-141240-01Hydroxy-PEG2-C2-methyl ester
HY-141045-01N- (m-PEG4) -N'- (PEG2-NHS ester) -Cy5
HY-141069N- (m-PEG4) -N'- (Biotin-PEG2-amido-PEG4) -Cy5
HY-141049N-methyl-N'- (propargyl-PEG4) -Cy5
HY-141040N-methyl-N'-methyl-O- (m-PEG4) -O'- (acid-PEG5) -Cy5
HY-140497-01Hydroxy-PEG2-CH2COOH
HY-124380-01Hydroxy-PEG2-acid

Alternative Products

CatalogName
T18446-01N-Methyl-N'- (hydroxy-PEG2) -Cy5
MBS5771305N-Methyl-N'-(hydroxy-PEG2)-Cy5
MBS5771288N-(m-PEG4)-N'-(hydroxy-PEG2)-Cy5
T18429-01N- (m-PEG4) -N'- (hydroxy-PEG2) -Cy5
T18445-01N-Methyl-N'- (azido-PEG2-C5) -Cy5
MBS5771304N-Methyl-N'-(azido-PEG2-C5)-Cy5
MBS5771292N-(m-PEG4)-N'-(PEG2-acid)-Cy5
GTR19225199-01N- (m-PEG4) -N'- (PEG2-acid) -Cy5
MBS5771293N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
OR1039744N- (m-PEG4) -N'- (PEG2-NHS ester) -Cy5

Popular Products