Hydroxy-PEG2-C2-methyl ester

• Description:

  Hydroxy-PEG2-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Product Name Alternative:

  Methyl 3-[2- (2-hydroxyethoxy) ethoxy]propanoate

• UNSPSC:

  12352211

• Hazard Statement:

  H315, H319

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-peg2-c2-methyl-ester.html

• Purity:

  99.95

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC)CCOCCOCCO

• Molecular Formula:

  C8H16O5

• Molecular Weight:

  192.21

• Precautions:

  H315, H319

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers

• CAS Number:

  [457897-73-3]