Hydroxy-PEG2-C2-methyl ester

• Description :

  Hydroxy-PEG2-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• CAS Number :

  [457897-73-3]

• Product Name Alternative :

  Methyl 3-[2- (2-hydroxyethoxy) ethoxy]propanoate

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hydroxy-peg2-c2-methyl-ester.html

• Purity :

  99.95

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(OC)CCOCCOCCO

• Molecular Formula :

  C8H16O5

• Molecular Weight :

  192.21

• Precautions :

  H315, H319

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Alkyl/ether Linkers; PEG Linkers