N-Methyl-N'-(azido-PEG2-C5)-Cy5

N-Methyl-N'-(azido-PEG2-C5)-Cy5

• UNSPSC Description: N-Methyl-N'-(azido-PEG2-C5)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Methyl-N'-(azido-PEG2-C5)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-methyl-n-azido-peg2-c5-cy5.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCCOCCOCCN=[N+]=[N-])=O)C(C=CC=C4)=C4C3(C)C.[Cl-]
• Molecular Weight: 675.30
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported