N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5

CAT:

804-HY-141071

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CAS Number: 2107273-76-5
UNSPSC Description: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-m-peg4-n-dbco-peg4-cy5.html
Solubility: 10 mM in DMSO
Smiles: COCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C2N(CCOCCOCCOCCOCCC(NCCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O)C6=C(C=CC=C6)C/2(C)C)C(C)(C)C7=C1C=CC=C7.[Cl-]
Molecular Weight: 1087.78
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-141071	N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
HY-141036	N-(m-PEG4)-N'-(PEG4-acid)-Cy5
HY-141053	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
HY-141068	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
HY-141046	N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5
HY-140582	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
HY-141069	N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5
HY-141074	N-(m-PEG4)-N'-hydroxypropyl-Cy5
HY-141075	N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5
HY-141076	N-(m-PEG4)-N'-(PEG3-Mal)-Cy5