N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5

CAT:

804-HY-141068

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CAS Number: 2107273-58-3
UNSPSC Description: N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-m-peg4-n-m-peg4-o-m-peg4-o-azide-peg4-cy5.html
Solubility: 10 mM in DMSO
Smiles: COCCOCCOCCOCCOC1=CC2=C([N+](CCOCCOCCOCCOC)=C(/C=C/C=C/C=C3N(CCOCCOCCOCCOC)C4=C(C=C(OCCOCCOCCOCCOCCN=[N+]=[N-])C=C4)C/3(C)C)C2(C)C)C=C1.[Cl-]
Molecular Weight: 1238.93
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-141068	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
HY-141053	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
HY-141067	N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
HY-141052	N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
HY-141071	N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
HY-141036	N-(m-PEG4)-N'-(PEG4-acid)-Cy5
HY-141031	N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
HY-141078	N-(m-PEG4)-N'-(azide-PEG4)-Cy7
HY-141030	N-(m-PEG4)-N'-(azide-PEG4)-Cy3
HY-141046	N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5

Cat	Name
T18431-1g	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
T18431-1mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
T18431-5mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
T18431-50mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
T18431-10mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
T18432-50mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
T18432-5mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
T18432-1g	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
T18432-10mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
T18432-1mg	N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5