N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5

• CAS Number: 2107273-58-3
• UNSPSC Description: N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-m-peg4-n-m-peg4-o-m-peg4-o-azide-peg4-cy5.html
• Solubility: 10 mM in DMSO
• Smiles: COCCOCCOCCOCCOC1=CC2=C([N+](CCOCCOCCOCCOC)=C(/C=C/C=C/C=C3N(CCOCCOCCOCCOC)C4=C(C=C(OCCOCCOCCOCCOCCN=[N+]=[N-])C=C4)C/3(C)C)C2(C)C)C=C1.[Cl-]
• Molecular Weight: 1238.93
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported