M-PEG8-DSPE

• Description:

  M-PEG8-DSPE is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352200

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Liposome; PROTAC Linkers

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease; PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg8-dspe.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCCCCCCCCCCC(OCC(COP(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)(O)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O

• Molecular Formula:

  C59H116NO17P

• Molecular Weight:

  1142.52

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers