M-PEG10-amine

• Description:

  M-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg10-amine.html

• Purity:

  99.97

• Solubility:

  10 mM in DMSO

• Smiles:

  COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

• Molecular Formula:

  C21H45NO10

• Molecular Weight:

  471.58

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Jennifer Riggs-Sauthier, et al. Polymer-semaxanib moiety conjugates. US20140011855A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Non-cleavable Linker; PEG Linkers

• CAS Number:

  [1383658-09-0]