Plasma kallikrein-IN-1

CAT:

804-HY-139888

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CAS Number: 2691030-28-9
UNSPSC Description: Plasma kallikrein-IN-1 is a PKK inhibitor with an IC50 value of 0.5 nM.
Target Antigen: Kallikrein
Type: Reference compound
Related Pathways: Immunology/Inflammation
Applications: Metabolism-protein/nucleotide metabolism
Field of Research: Endocrinology
Assay Protocol: https://www.medchemexpress.com/plasma-kallikrein-in-1.html
Solubility: 10 mM in DMSO
Smiles: FC(F)C1=C(C=CC(N2CC3(CC3)C2)=N1)CN4C=NC(C(N[C@@H]5CCC6=C(C)NN=C65)=O)=C4
Molecular Weight: 453.49
References & Citations: [1]Sabnis RW. Novel Heteroaromatic Carboxamides as Plasma Kallikrein Inhibitors for Treating Diabetic Complications, Ocular Diseases, and Edema-Associated Diseases. ACS Med Chem Lett. 2021 Oct 21;12(11):1637-1638.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-139888	Plasma kallikrein-IN-1
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HY-150052	Plasma kallikrein-IN-3
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