Antibacterial agent 63

• UNSPSC Description:

  Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-63.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=NC(/C(C(N[C@@H]2C(N(S(O)(=O)=O)[C@H]2C)=O)=O)=N/OC(C(NCCNC(CN(C(C3=CC=CC(O)=C3O)=O)CCCCNC(C4=CC=CC(O)=C4O)=O)=O)=O)(C)C)=CS1

• Molecular Weight:

  877.90

• References & Citations:

  [1]Liu R, et al. Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria. ACS Infect Dis. 2021 Nov 12;7(11):2979-2986.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4