Antibacterial agent 63

• Description :

  Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antibacterial-agent-63.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=NC(/C(C(N[C@@H]2C(N(S(O)(=O)=O)[C@H]2C)=O)=O)=N/OC(C(NCCNC(CN(C(C3=CC=CC(O)=C3O)=O)CCCCNC(C4=CC=CC(O)=C4O)=O)=O)=O)(C)C)=CS1

• Molecular Formula :

  C35H43N9O14S2

• Molecular Weight :

  877.90

• References & Citations :

  [1]Liu R, et al. Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria. ACS Infect Dis. 2021 Nov 12;7 (11) :2979-2986.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2910919-43-4]