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CBP/p300-IN-14

CAT: 0804-HY-139861Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139861Size:1 Each
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Description
CBP/p300-IN-14 is a potent inhibitor of CBP/EP300 (lysine acetyltransferase) with an IC50 of 3.3 nM (extracted from patent WO2021213521A1, compound 27) [1].
CAS Number
2725036-10-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Epigenetic Reader Domain; Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbp-p300-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=CC(N3C(CN(CC3)C)=O)=C2)C(N4C5=C(CCC4)C=C(C6=CN(C)N=C6)C(C(F)F)=C5)=N1)NC
Molecular Formula
C30H31F2N7O2
Molecular Weight
559.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Wang, Lisha, et al. Cbp/ep300 inhibitor and use thereof. Patent WO2021213521A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CBP/p300

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