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CBP/p300-IN-2

CAT: 0804-HY-128761Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-128761Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 with IC50 values of 1.07 nM and 5.96 nM for CBP/HTRF and Myc, respectively. CBP/EP300-IN-2, example 25, is extracted from patent WO2017205538A1[1].
CAS Number
2158265-96-2
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbp-ep300-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(N(C2CCOCC2)N=C3C4=CN=CC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)NC
Molecular Formula
C27H29F2N7O2
Molecular Weight
521.56
References & Citations
[1]Patrick Cyr, et al. Pyrazolopyridine derivatives for the treatment of cancer
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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