MK-4688

• UNSPSC Description:

  MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mk-4688.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H](CC1)CC[C@H]1CN(C(N2CCO[C@H]3[C@H]2CCC3)=N4)C5=C4C=C(C(N6)=NOC6=O)N=C5C7=CC(Cl)=CN=C7

• Molecular Weight:

  550.05

• References & Citations:

  [1]Reutershan MH, et al. Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction. J Med Chem. 2021 Nov 11;64(21):16213-16241.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1616428-79-5