NI-Pano

CAT: 0804-HY-139701Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-139701Size:1 Each

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Description

NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor. NI-Pano (CH-03) is reduced in an O2-dependent manner to release panobinostat.

CAS Number

2733559-66-3

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ni-pano.html

Solubility

10 mM in DMSO

Smiles

CC(N1)=C(CCNCC2=CC=C(/C=C/C(NOCC3=CN=C([N+]([O-])=O)N3C)=O)C=C2)C4=C1C=CC=C4

Molecular Formula

C26H28N6O4

Molecular Weight

488.54

References & Citations

[1]Skwarska A, et al. Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor. Cell Chem Biol. 2021 Sep 16;28 (9) :1258-1270.e13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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HY-101121-01	NI-42
HY-19537-01	NI-57
HY-K0238-01	Ni-IDA Agarose
HY-101121R	NI-42 (Standard)
HY-170779	DOTA-NI-FAPI-04

Alternative Products

Catalog	Name
T63258-01	NI-Pano
AM31707AF-N	Human IgG, IgA, IgM, IgD, IgE Mouse Monoclonal Antibody [Clone ID: NI 335 and NI 343, NI 69 and NI 184, NI 179, NI 158, NI 307]
T9901A-1598-01	NI-301
406993	NI-42
407351	NI-57
P0413	PTALEN_v2 (NI)
JAD64099-01	NI 42
BN166032-01	NI 57
T9901A-993-01	NI-203
T9901A-1621-01	NI-006

NI-Pano

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