Pomalidomide 4'-PEG5-azide

Pomalidomide 4'-PEG5-azide

• CAS Number: 2624181-61-7
• UNSPSC Description: Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-4-peg5-azide.html
• Solubility: 10 mM in DMSO
• Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
• Molecular Weight: 562.57
• References & Citations: [1]Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19(1):166-170.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported