Pomalidomide-PEG5-Alkyne

• Target:

  Ligands for Target Protein for PROTAC

• Related Pathways:

  PROTAC

• Bioactivity:

  Pomalidomide-PEG5-Alkyne serves as a key building block in the synthesis of targeted protein degraders and PROTACs. This compound includes a (CRBN) -recruiting ligand and a PEGylated crosslinker that features a pendant alkyne, which facilitates click chemistry reactions with an azide on the target ligand.

• Smiles:

  C#CCOCCOCCOCCOCCOCCC(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O

• Molecular Formula:

  C27H33N3O10

• Molecular Weight:

  559.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C