20-O-Demethyl-AP3

• UNSPSC Description:

  20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/20-o-demethyl-ap3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC(C(C)C)=O)=O)C)=C(C(O)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1

• Molecular Weight:

  621.12

• References & Citations:

  [1]Zhongfa Liu, et al. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. J Mass Spectrom. 2005 Mar;40(3):389-99.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  72902-38-6