7-O-Demethyl rapamycin

• UNSPSC Description:

  7-O-Demethyl rapamycin, a derivative of Rapamycin (HY-10219), has antifungal activity and immunosuppressant properties. 7-O-Demethyl rapamycin has useful tumor cell growth-inhibiting activity[1].

• Target Antigen:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/7-o-demethyl-rapamycin.html

• Purity:

  97.59

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]1(O[C@@](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C2=O)C)C)O)([H])CC[C@H]1C)C(C(N(CCCC3)[C@]3([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H]2OC)O)\C)C)=O)([H])[C@H](C)C[C@H](CC[C@H]4O)C[C@H]4OC)=O)=O)=O

• Molecular Weight:

  900.15

• References & Citations:

  [1]James Amigo Chan, et al. Process for producing rapamycin derivatives. WO1994012655A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  151519-50-5