L-AP3

CAT: 0804-HY-108546-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-108546-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-AP3, metabotropic glutamate receptor (mGluR) antagonist, inhibits D-phosphoserine and L-phosphoserine with IC50s of 368 μM and 2087 μM, respectively[1].
CAS Number
[23052-80-4]
Product Name Alternative
3-Phosphono-L-alanine
UNSPSC
12352211
Hazard Statement
H302, H312, H332
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-ap3.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
N[C@@H](CP(O)(O)=O)C(O)=O
Molecular Formula
C3H8NO5P
Molecular Weight
169.07
Precautions
H302, H312, H332
References & Citations
[1]J E Hawkinson, et al. The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase. Eur J Pharmacol. 1996 Jun 27;307 (2) :219-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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