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7-Hydroxyquetiapine

CAT: 0804-HY-137532Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137532Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Hydroxyquetiapine (ICI 214227) is the major active metabolite of antipsychotic medicine Quetiapine[1].
CAS Number
139079-39-3
Product Name Alternative
ICI 214227
UNSPSC
12352005
Hazard Statement
H225-H301+H311+H331-H370
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-hydroxyquetiapine.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C2C(SC3=CC=CC=C3C(N4CCN(CCOCCO)CC4)=N2)=C1
Molecular Formula
C21H25N3O3S
Molecular Weight
399.51
Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Bakken GV, et al. Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5. Drug Metab Dispos. 2009 Feb;37 (2) :254-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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