Meropenem-d6-1

• UNSPSC Description :

  Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1].

• Target Antigen :

  Antibiotic; Bacterial

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  infection

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(N12)=C(S[C@@H]3CN[C@H](C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O

• Molecular Weight :

  389.50

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]L Slaney, et al. In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother. 1989 Sep;24 Suppl A:183-6.

• Shipping Conditions :

  Room temperature

• Clinical Information :

  No Development Reported

• CAS Number :

  [1133424-00-6]