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Meropenem-d6

CAT: 0804-HY-13678S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13678S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) [1][2].
CAS Number
1217976-95-8
Product Name Alternative
SM 7338-d6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
98.28
Solubility
DMSO : 100mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C(C(O)=O)N1C([C@]([C@@H](C)O)2[H])=O
Molecular Formula
C17H19D6N3O5S
Molecular Weight
389.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]L Slaney, et al. In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother. 1989 Sep;24 Suppl A:183-6.|[3]George G Zhanel, et al. Comparative review of the carbapenems. Drugs. 2007;67 (7) :1027-52.|[4]Umit Ateskan, et al. Deferoxamine and meropenem combination therapy in experimental acute pancreatitis. Pancreas. 2003 Oct;27 (3) :247-52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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