Meropenem-d6

Meropenem-d6

• CAS Number: 1217976-95-8
• UNSPSC Description: Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
• Target Antigen: Antibiotic; Bacterial
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection
• Field of Research: Infection
• Smiles: [H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C(C(O)=O)N1C([C@]([C@@H](C)O)2[H])=O
• Molecular Weight: 389.50
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]L Slaney, et al. In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother. 1989 Sep;24 Suppl A:183-6.|[3]George G Zhanel, et al. Comparative review of the carbapenems. Drugs. 2007;67(7):1027-52.|[4]Umit Ateskan, et al. Deferoxamine and meropenem combination therapy in experimental acute pancreatitis. Pancreas. 2003 Oct;27(3):247-52.
• Shipping Conditions: Blue Ice