Rabacfosadine (succinate)

• UNSPSC Description:

  Rabacfosadine (GS-9219) succinate, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rabacfosadine-succinate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCC(O)=O)=O.CCOC([C@H](C)NP(COCCN1C2=NC(N)=NC(NC3CC3)=C2N=C1)(N[C@@H](C)C(OCC)=O)=O)=O

• Molecular Weight:

  644.61

• References & Citations:

  [1]Reiser H, et al. GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma. Clin Cancer Res. 2008 May 1;14(9):2824-32.|[2]De Clercq E. Tanovea® for the treatment of lymphoma in dogs. Biochem Pharmacol. 2018 Aug;154:265-269.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  1431856-99-3