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Fulvestrant-d5

CAT: 0804-HY-13636S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13636S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fulvestrant-d5 (ICI 182780-d5) is a isotope of Fulvestrant. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.
Product Name Alternative
ICI 182780-d5; ZD 9238-d5; ZM 182780-d5
UNSPSC
12352005
Hazard Statement
H303, H315, H360, H362, H410
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Purity
99.66
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]([2H])(C([2H])(C[C@]1([C@@]3([C@@H](CC4=C([C@]3(CC2)[H])C=C(C(O)=C4[2H])[2H])CCCCCCCCCS(CCCC(F)(C(F)(F)F)F)=O)[H])[H])[2H])O
Molecular Formula
C32H42D5F5O3S
Molecular Weight
611.80
Precautions
H303, H315, H360, H362, H410
References & Citations
[1]Wakeling AE, et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991 Aug 1;51 (15) :3867-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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