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Fulvestrant (Standard)

CAT: 0804-HY-13636R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13636R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy[1].
CAS Number
129453-61-8
Product Name Alternative
ICI 182780 (Standard) ; ZD 9238 (Standard) ; ZM 182780 (Standard)
UNSPSC
12352005
Hazard Statement
H360, H362, H413
Target
Apoptosis; Autophagy; Estrogen Receptor/ERR; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fulvestrant-standard.html
Purity
99.71
Smiles
C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2
Molecular Formula
C32H47F5O3S
Molecular Weight
606.77
Precautions
H360, H362, H413
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported

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